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  • CRISPR/Cas9 System Background

    CRISPR/Cas9 System Background | OHSU Genome Editing via CRISPR/Cas9 system Background The following paragraph is short description from "Mouse Genome Editing Using the CRISPR/Cas System" Donald W. Harms, Rolen M. Quadros, Davide Seruggia, Masato Ohtsuka, Gou Takahashi, Lluis...

  • CRISPR Microinjection

    CRISPR Microinjection | OHSU Genome Editing via CRISPR/Cas9 System Click here to see the background on Genome Editing via CRISPR/Cas9 System. Resources and recommendations Project initiation Before initiating a CRISPR/Cas9 mouse project please Consult with the TMM Core...

  • OHSU performs first-ever CRISPR gene editing within human body | OHSU News

    OHSU performs first-ever CRISPR gene editing within human body | OHSU News Share Tweet Share Email Print OHSU performs first-ever CRISPR gene editing within human body BRILLIANCE clinical trial aims to enable sight in people born with a blindness...

  • News from OHSU Casey Eye Institute

    ...OHSU’s involvement in the clinical trial, which is the first time scientists are using the gene-editing technique CRISPR inside the human body. Read the story . Oregon donors help OHSU expand access to eye exams, treatment and education statewide...

  • Innovations: Advancing Surgery 2021

    ...Advancing Surgery 2021 | OHSU Casey Eye Institute operating room team prepares to deliver first invivo gene editing treatment using CRISPR/Cas9 technology in human. Photo courtesy of Kristyna Wentz-Graff. Pioneering the first-ever CRISPR gene editing in vivo On...

  • Center for Embryonic Cell and Gene Therapy

    ...later (2018), the initial confirmation that a dangerous genetic defect can in theory be erased. Science News editors identified "CRISPR gene editing moves into humans, spurs debate" as their Number 2 story of 2017 - @ScienceNews' top stories of 2017! #SNTop10...

  • Research

    ...loss of function aberrations. To address this shortcoming, our lab has recently developed and optimized a workflow that couples CRISPR/Cas screening with a sensitive cellular transformation assay to identify loss-of-function genes that yield growth factor independence and...

  • Lab Members | Freeman Lab

    Lab Members | Freeman Lab | OHSU Current lab members Leire Abalde-Atristain, Ph.D. abaldeat@ohsu.edu Postdoctoral Fellow Born in the beautiful town of San Sebastian in the Basque Country (Northern Spain), Leire received her B.Sc. in Biotechnology fro

  • Previous Research Weeks

    ...OHSU Auditorium OHSU researchers have been at the forefront of gene repair techniques, including the first demonstration of the CRISPR technique to repair a disease-causing mutation in humans. The international community, led in part by OHSU faculty, has called...

  • About

    ...with over five hundred unique transgenic and knockout mouse lines produced. The Core currently provides technology and expertise in CRISPR genome editing. Maintaining pace with the exponential growth in transgenic technology, our staff regularly attend courses, workshops, and conferences at...